4Ībilify tablets are available in strengths of 2 mg, 5 mg, 10 mg, 15 mg, 20 mg, and 30 mg. The oral solution is flavored with natural orange cream and other natural flavors. The inactive ingredients for this solution include disodium edetate, fructose, glycerin, dl-lactic acid, methylparaben, propylene glycol, propylparaben, sodium hydroxide, sucrose, and purified water. 1Ĭommercially available Abilify Oral Solution is a clear, colorless to light-yellow solution available in a concentration of 1 mg/mL. Aripiprazole is available as tablets, orally disintegrating tablets, oral solution, and injection. 3ĭiscussion: Aripiprazole (Abilify, MW 448.39, C 23H 27Cl 2N 3O 2) is an atypical antipsychotic that occurs as a white to off-white, crystalline powder. Quality Control: Quality-control assessment can include weight/volume, pH, specific gravity, active drug assay, color, rheologic properties/pourability, physical observation, and physical stability (discoloration, foreign materials, gas formation, mold growth). Stability: A beyond-use date of up to 91 days may be used for this preparation. Packaging: Package in tight, light-resistant, child-resistant containers. This formulation may be used in patients who cannot take the solid oral dosage forms or tolerate any of the ingredients in the commercially available aripiprazole oral solution. Use: Aripiprazole oral solution is used in the treatment of schizophrenia, the acute treatment of manic and mixed episodes associated with bipolar disorder, the adjunctive treatment of major depressive disorder, irritability associated with autistic disorder, and the treatment of Tourette syndrome. As an alternative to the combination of Ora-Plus and Ora-Sweet, Ora-Blend may be used as the vehicle. Incorporate sufficient Ora-Sweet to final volume and mix well. Geometrically, add the remainder of the Ora-Plus, with thorough mixing after each addition. Combine the aripiprazole with a few milliliters of Ora-Plus and mix to form a smooth paste. Accurately weigh or measure each ingredient. Method of Preparation: Calculate the quantity of each ingredient needed.
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